Divers diving DUI Silicone ZipSeals report them to be more comfortable overall and for many provide a dryer seal on the wrist. Silicone is also ideal for people with latex allergies. The downside to silicone is that they can be more prone to tearing and punctures so care should be used when handling. The outside of the seals tend to gather more dirt as well.
The greatest benefit to latex seals is that they are more durable overall. If you do not live in a high UV or ozone climate, latex might be the best option for you.
I found this information on the web for you, hopefully you find it helpful, I have honestly never used a Dry Suit.